9SWJ

Human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2 bound to coenzyme A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (C, A, E, G)	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial	polymer	305	32161.9	4	UniProt (P53597) Pfam (PF02629) Pfam (PF00549)	Homo sapiens (human)	Succinyl-CoA synthetase subunit alpha,SCS-alpha
2	B, D, F, H (D, B, F, H)	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	polymer	437	47757.0	4	UniProt (Q9P2R7) Pfam (PF08442) Pfam (PF00549)	Homo sapiens (human)	ATP-specific succinyl-CoA synthetase subunit beta,A-SCS,Succinyl-CoA synthetase beta-A chain,SCS-betaA
3	I, J, K, L (C, A, E, G)	COENZYME A	non-polymer		767.5	4	Chemie (COA)

Sequence modifications

D, B, F, H: 52 - 463 (UniProt: Q9P2R7)

PDB	External Database	Details
Met 29	-	initiating methionine
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
Ser 36	-	expression tag
Ser 37	-	expression tag
Gly 38	-	expression tag
Val 39	-	expression tag
Asp 40	-	expression tag
Leu 41	-	expression tag
Gly 42	-	expression tag
Thr 43	-	expression tag
Glu 44	-	expression tag
Asn 45	-	expression tag
Leu 46	-	expression tag
Tyr 47	-	expression tag
Phe 48	-	expression tag
Gln 49	-	expression tag
Ser 50	-	expression tag
Met 51	-	expression tag
Trp 464	-	expression tag
Gln 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	319675.5
Non-Polymers*	Number of molecules	4
	Total formula weight	3070.1
All*	Total formula weight	322745.7

*Water molecules are not included.