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9SPS

p53 cancer mutant E285K in complex with DARPin C10-H82R

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cellular tumor antigen p53polymer20222721.81UniProt (P04637)
Pfam (PF00870)
Homo sapiens (human)Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
2B
(E)
DARPin C10-H82Rpolymer12613546.31synthetic construct
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
5E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
PubChem (32051)
6F, G
(A, E)
waterwater18.0333Chemie (HOH)
Sequence modifications
A: 94 - 294 (UniProt: P04637)
PDBExternal DatabaseDetails
Ser 93-expression tag
Lys 285Glu 285variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36268.2
Non-Polymers*Number of molecules3
Total formula weight223.5
All*Total formula weight36491.7
*Water molecules are not included.

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PDB entries from 2026-07-29

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