9SH7
Crystal structure of DENV3 NS5 methyltransferase domain in complex with TO335 inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Genome polyprotein | polymer | 258 | 29314.8 | 2 | UniProt (C0LMU0) | dengue virus type 3 | |
| 2 | C (A) | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[[1-[(3-fluorophenyl)methyl]-1,2,3-triazol-4-yl]methyl]amino]-2-azanyl-butanoic acid | non-polymer | 556.5 | 1 | Chemie (A1JNS) | |||
| 3 | D (C) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (439155) | |||
| 4 | E, F (A, C) | water | water | 18.0 | 709 | Chemie (HOH) |
Sequence modifications
A, C: 6 - 262 (UniProt: C0LMU0)
| PDB | External Database | Details |
|---|---|---|
| Ser 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58629.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 941.0 | |
| All* | Total formula weight | 59570.6 |
