9SG0
CJM112 Fv in complex with human IL-17A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-17A | polymer | 138 | 15919.9 | 1 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (human) | IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | B (H) | CJM112 Fv heavy-chain | polymer | 122 | 13723.2 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | CJM112 Fv light-chain | polymer | 115 | 12653.0 | 1 | Homo sapiens (human) | ||
| 4 | D (H) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A: 24 - 155 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Glu 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Arg 20 | - | expression tag |
| His 21 | - | expression tag |
| Asp 22 | - | expression tag |
| Ser 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 42296.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 42392.2 |
