9SBB
Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | TAU-2310 Fab Heavy Chain | polymer | 229 | 24084.8 | 1 | Homo sapiens | ||
| 2 | B (L) | TAU-2310 Fab Light Chain | polymer | 217 | 22906.1 | 1 | Homo sapiens | ||
| 3 | C (R) | Spike protein S1 | polymer | 219 | 24716.8 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Homo sapiens (human) | |
| 4 | D, H, I (L, R) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 5 | E (L) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 6 | F (L) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) PubChem (28486) | |||
| 7 | G (R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 8 | J, K, L (H, L, R) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
R: 327 - 535 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Pro 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Thr 538 | - | expression tag |
| Lys 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
| His 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71707.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 610.6 | |
| All* | Total formula weight | 72318.3 |
