9SAT
Monoclonal Antibodies from COVID-19 Convalescent Patients Target Cryptic Epitopes for Universal SARS-CoV-2 Neutralization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | TAU-1109 Fab Heavy Chain | polymer | 225 | 24067.9 | 1 | Homo sapiens | ||
| 2 | B (L) | TAU-1109 Fab Light Chain | polymer | 216 | 23679.4 | 1 | Homo sapiens | ||
| 3 | C (R) | Spike protein S1 | polymer | 266 | 29422.9 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 4 | D, E, F (H, L) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | G, H, I (H, L, R) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
R: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 542 | - | expression tag |
| Gly 543 | - | expression tag |
| Arg 544 | - | expression tag |
| Leu 545 | - | expression tag |
| Glu 546 | - | expression tag |
| Val 547 | - | expression tag |
| Leu 548 | - | expression tag |
| Phe 549 | - | expression tag |
| Gln 550 | - | expression tag |
| Gly 551 | - | expression tag |
| Pro 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Ser 554 | - | expression tag |
| Ala 555 | - | expression tag |
| Trp 556 | - | expression tag |
| Ser 557 | - | expression tag |
| His 558 | - | expression tag |
| Pro 559 | - | expression tag |
| Gln 560 | - | expression tag |
| Phe 561 | - | expression tag |
| Glu 562 | - | expression tag |
| Lys 563 | - | expression tag |
| Gly 564 | - | expression tag |
| Gly 565 | - | expression tag |
| Gly 566 | - | expression tag |
| Ser 567 | - | expression tag |
| Gly 568 | - | expression tag |
| Gly 569 | - | expression tag |
| Gly 570 | - | expression tag |
| Gly 571 | - | expression tag |
| Ser 572 | - | expression tag |
| Gly 573 | - | expression tag |
| Gly 574 | - | expression tag |
| Ser 575 | - | expression tag |
| Ala 576 | - | expression tag |
| Trp 577 | - | expression tag |
| Ser 578 | - | expression tag |
| His 579 | - | expression tag |
| Pro 580 | - | expression tag |
| Gln 581 | - | expression tag |
| Phe 582 | - | expression tag |
| Glu 583 | - | expression tag |
| Lys 584 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 77170.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 77366.4 |
