9SA7
Crystal structure of Methanocaldococcus jannaschii Malate dehydrogenase C7 mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, C) | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | polymer | 313 | 34550.1 | 4 | UniProt (Q60176) Pfam (PF00056) Pfam (PF02866) | Methanocaldococcaceae | MdhII |
| 2 | E, F, G, H (A, B, D, C) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) |
Sequence modifications
A, B, D, C: 1 - 313 (UniProt: Q60176)
| PDB | External Database | Details |
|---|---|---|
| Lys 42 | Glu 42 | engineered mutation |
| Met 46 | Glu 46 | engineered mutation |
| Asn 105 | Lys 105 | engineered mutation |
| Glu 135 | Asp 135 | engineered mutation |
| Lys 140 | Arg 140 | engineered mutation |
| Arg 198 | Lys 198 | engineered mutation |
| Tyr 217 | Lys 217 | engineered mutation |
| Lys 219 | Glu 219 | engineered mutation |
| Asp 223 | Arg 223 | engineered mutation |
| Lys 277 | Arg 277 | engineered mutation |
| Asn 289 | Asp 289 | engineered mutation |
| Gly 305 | Lys 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138200.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2981.7 | |
| All* | Total formula weight | 141182.2 |
