9RYL
METTL1 bound to the SAM competitive small molecule inhibitor STM9005
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA (guanine-N(7)-)-methyltransferase | polymer | 235 | 27035.0 | 1 | UniProt (Q9UBP6) Pfam (PF02390) | Homo sapiens (human) | Methyltransferase-like protein 1,mRNA (guanine-N(7)-)-methyltransferase,miRNA (guanine-N(7)-)-methyltransferase,tRNA (guanine(46)-N(7))-methyltransferase,tRNA(m7G46)-methyltransferase |
| 2 | B (A) | [(2~{R})-4-(2-azanyl-[1,3]oxazolo[4,5-c]pyridin-7-yl)morpholin-2-yl]-[(1~{S})-6,8-bis(chloranyl)-1-methyl-3,4-dihydro-1~{H}-isoquinolin-2-yl]methanone | non-polymer | 462.3 | 1 | Chemie (A1JKJ) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | I (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | J (A) | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A: 32 - 265 (UniProt: Q9UBP6)
| PDB | External Database | Details |
|---|---|---|
| Gly 31 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27035.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 938.2 | |
| All* | Total formula weight | 27973.2 |
