9RXQ

Structure of the PDZ1 domain from human NHERF1 with the C-terminal residues (KSTQF) of human URAT1 transporter (SLC22A12)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Solute carrier family 22 member 12	polymer	90	9818.2	2	UniProt (O14745) UniProt (Q96S37)	Homo sapiens (human)	NHERF-1,Ezrin-radixin-moesin-binding phosphoprotein 50,EBP50,Regulatory cofactor of Na(+)/H(+) exchanger,Sodium-hydrogen exchanger regulatory factor 1,Solute carrier family 9 isoform A3 regulatory factor 1,Organic anion transporter 4-like protein,Renal-specific transporter,RST,Urate anion exchanger 1,URAT1,Urate:anion antiporter SLC22A12
2	C (B)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
3	D, E (A, B)	water	water		18.0	244	Chemie (HOH)

Sequence modifications

A, B: 11 - 94 (UniProt: O14745)

PDB	External Database	Details
Gly 10	-	expression tag

A, B: 95 - 99 (UniProt: Q96S37)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	19636.5
Non-Polymers*	Number of molecules	1
	Total formula weight	59.0
All*	Total formula weight	19695.5

*Water molecules are not included.