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9RTT

Activated Elongation Complex with IWS1 and ELOF1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
RNA polymerase II subunit Dpolymer14216331.31UniProt (A0A287ADR4)
Pfam (PF03874)
Sus scrofa (pig)
2B
(E)
DNA-directed RNA polymerase II subunit Epolymer21024644.31UniProt (I3LSI7)
Pfam (PF03871)
Pfam (PF01191)
Sus scrofa (pig)RPB5 homolog
3C
(F)
DNA-directed RNA polymerases I, II, and III subunit RPABC2polymer12714477.01UniProt (A0A8D1KNW4)
Pfam (PF01192)
Sus scrofa (pig)
4D
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17219314.31UniProt (A0A4X1VKG7)
Pfam (PF03876)
Pfam (PF00575)
Sus scrofa (pig)
5E
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer15017162.31UniProt (I3LCB2)
Pfam (PF03870)
Sus scrofa (pig)
6F
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12514541.21UniProt (P60899)
Pfam (PF02150)
Pfam (PF01096)
Sus scrofa (pig)RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
7G
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer677655.11UniProt (A0A4X1VYD0)
Pfam (PF01194)
Sus scrofa (pig)
8H
(K)
DNA-directed RNA polymerase II subunit RPB11-apolymer11713310.31UniProt (F1RKE4)
Pfam (PF13656)
Sus scrofa (pig)
9I
(L)
RNA polymerase II subunit Kpolymer587018.21UniProt (A0A8D0JYF1)
Pfam (PF03604)
Sus scrofa (pig)
10J
(P)
RNApolymer216636.91synthetic construct
11K
(Q)
RNA polymerase-associated protein CTR9 homologpolymer1179134510.21UniProt (Q6PD62)
Pfam (PF13374)
Pfam (PF13181)
Homo sapiens (human)SH2 domain-binding protein 1
12L
(T)
Template DNApolymer25778779.31synthetic construct
13M
(W)
Superkiller complex protein 8polymer30533617.51UniProt (Q9GZS3)
Pfam (PF00400)
Homo sapiens (human)Ski8,Meiotic recombination REC14 protein homolog,WD repeat-containing protein 61
14N
(Y)
Transcription elongation factor SPT4polymer12113508.51UniProt (P63272)
Pfam (PF06093)
Homo sapiens (human)hSPT4,DRB sensitivity-inducing factor 14 kDa subunit,DSIF p14,DRB sensitivity-inducing factor small subunit,DSIF small subunit
15O
(b)
Transcription elongation factor 1 homologpolymer859616.91UniProt (P60002)
Pfam (PF05129)
Homo sapiens (human)
16P
(A)
DNA-directed RNA polymerase subunitpolymer1970217610.01UniProt (A0A8D1DPV6)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Sus scrofa (pig)
17Q
(B)
DNA-directed RNA polymerase subunit betapolymer1174134041.41UniProt (I3LGP4)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Sus scrofa (pig)
18R
(C)
DNA-directed RNA polymerase II subunit RPB3polymer27531439.11UniProt (I3LCH3)
Pfam (PF01193)
Pfam (PF01000)
Sus scrofa (pig)
19S
(M)
Transcription elongation factor SPT6polymer1729199603.01UniProt (Q7KZ85)
Pfam (PF14632)
Pfam (PF14641)
Pfam (PF22706)
Pfam (PF14639)
Pfam (PF14635)
Pfam (PF17674)
Pfam (PF00575)
Pfam (PF14633)
Homo sapiens (human)hSPT6,Histone chaperone suppressor of Ty6,Tat-cotransactivator 2 protein,Tat-CT2 protein
20T
(N)
Non-template DNApolymer24776916.61synthetic construct
21U
(U)
RNA polymerase-associated protein LEO1polymer66675514.21UniProt (Q8WVC0)
Pfam (PF04004)
Homo sapiens (human)Replicative senescence down-regulated leo1-like protein
22V
(V)
RNA polymerase II-associated factor 1 homologpolymer53160052.71UniProt (Q8N7H5)
Pfam (PF03985)
Homo sapiens (human)hPAF1,Pancreatic differentiation protein 2
23W
(X)
Parafibrominpolymer53160673.51UniProt (Q6P1J9)
Pfam (PF16050)
Pfam (PF05179)
Homo sapiens (human)Cell division cycle protein 73 homolog,Hyperparathyroidism 2 protein
24X
(Z)
Transcription elongation factor SPT5polymer1087121145.51UniProt (O00267)
Pfam (PF11942)
Pfam (PF03439)
Pfam (PF00467)
Homo sapiens (human)hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein
25Y
(a)
Protein IWS1 homologpolymer82192235.91UniProt (Q96ST2)
Pfam (PF08711)
Homo sapiens (human)IWS1-like protein
26AA, BA, CA, DA, EA...
(I, J, L, Y, A...)
ZINC IONnon-polymer65.49Chemie (ZN)
27GA
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence modifications
Q: 1 - 1173 (UniProt: Q6PD62)
PDBExternal DatabaseDetails
Glu 1174-expression tag
Asn 1175-expression tag
Leu 1176-expression tag
Tyr 1177-expression tag
Phe 1178-expression tag
Gln 1179-expression tag
Y: 1 - 117 (UniProt: P63272)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
b: 2 - 83 (UniProt: P60002)
PDBExternal DatabaseDetails
Ser -1-expression tag
Asn 0-expression tag
Ala 1-expression tag
M: 1 - 1726 (UniProt: Q7KZ85)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
a: 2 - 819 (UniProt: Q96ST2)
PDBExternal DatabaseDetails
Ser -1-expression tag
Asn 0-expression tag
Ala 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains25
Total formula weight1480355.2
Non-Polymers*Number of molecules10
Total formula weight613.0
All*Total formula weight1480968.2
*Water molecules are not included.

245011

PDB entries from 2025-11-19

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