9RP9
Crystal structure of mouse pVHL-ElonginB-ElonginC complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | von Hippel-Lindau disease tumor suppressor | polymer | 164 | 19019.6 | 1 | UniProt (Q3TTE7) Pfam (PF01847) Pfam (PF17211) UniProt (by SIFTS) (P40338) | Mus musculus (house mouse) | pVHL |
| 2 | B (B) | Elongin-B | polymer | 104 | 11816.5 | 1 | UniProt (P62869) Pfam (PF00240) | Mus musculus (house mouse) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 3 | C (C) | Elongin-C | polymer | 97 | 10974.6 | 1 | UniProt (P83940) Pfam (PF03931) | Mus musculus (house mouse) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Stromal membrane-associated protein SMAP1B homolog,Transcription elongation factor B polypeptide 1 |
| 4 | D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | E, G, I (A, B, C) | IODIDE ION | non-polymer | 126.9 | 3 | Chemie (IOD) | |||
| 6 | F, H, K, L (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | J (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | M, N, O (A, B, C) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 20 - 181 (UniProt: Q3TTE7)
C: 17 - 112 (UniProt: P83940)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41810.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 885.3 | |
| All* | Total formula weight | 42696.0 |
