9RMX
CryoEM reconstruction of integrase filament at the lumen of native HIV-1 cores (box size 34.2 nm)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Integrase | polymer | 288 | 32242.8 | 12 | UniProt (P12497) | Human immunodeficiency virus 1 | IN |
| 2 | AA, BA, CA, DA, EA... (U, V, W, X, Y...) | Gag polyprotein | polymer | 231 | 25630.4 | 32 | UniProt (Q72497) | Human immunodeficiency virus 1 | |
| 3 | AB, BB, CB, DB, SA... (I, J, K, L, A...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 4 | EB, FB, GB, HB, IB... (X, Z, a, b, g...) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 8 | Chemie (IHP) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 288 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Asn 64 | Asp 1211 | engineered mutation |
| Asn 116 | Asp 1263 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 44 |
| Total formula weight | 1207087.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 6065.2 | |
| All* | Total formula weight | 1213152.6 |
