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9RMR

Crystal structure of RXR alpha LBD bound to a synthetic agonist FN558 and a coactivator fragment

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer23526353.61UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2B
(B)
Nuclear receptor coactivator 2polymer101276.51UniProt (Q15596)Homo sapiensNCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3C
(A)
FN558non-polymer469.41Chemie (A1JH6)
4D, E
(A, B)
waterwater18.0107Chemie (HOH)
Sequence modifications
A: 229 - 462 (UniProt: P19793)
PDBExternal DatabaseDetails
Ser 228-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27630.1
Non-Polymers*Number of molecules1
Total formula weight469.4
All*Total formula weight28099.5
*Water molecules are not included.

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PDB entries from 2025-09-24

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