9RMR

Crystal structure of RXR alpha LBD bound to a synthetic agonist FN558 and a coactivator fragment

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID23-2
Synchrotron site	ESRF
Beamline	ID23-2
Temperature [K]	200
Detector technology	PIXEL
Collection date	2025-05-30
Detector	DECTRIS EIGER2 X 9M
Wavelength(s)	0.8731
Spacegroup name	P 43 21 2
Unit cell lengths	64.401, 64.401, 112.173
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	42.300 - 1.650
R-factor	0.1938
Rwork	0.193
R-free	0.21490
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.004
RMSD bond angle	0.702
Data reduction software	XDS
Data scaling software	XSCALE
Phasing software	PHASER
Refinement software	PHENIX (1.21.1_5286)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	42.300	1.710
High resolution limit [Å]	1.650	1.650
Rmerge	0.129	1.268
Rmeas	0.134
Rpim	0.038	0.377
Number of reflections	29225	2844
<I/σ(I)>	12.3	1.84
Completeness [%]	100.0	99.82
Redundancy	12.2	12.1
CC(1/2)	0.999	0.692

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		277	20% PEG 3350, 0.1 M magnesium actetate