9RM2

BKPyV VP1 IN COMPLEX WITH 319C07-FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M (H, A, D, G, M)	319C07 antibody heavy chain, Fab fragment	polymer	223	24208.1	5		Homo sapiens
2	B, E, H, K, N (L, B, E, J, N)	319C07 antibody light chain, Fab fragment	polymer	215	23297.9	5		Homo sapiens
3	C, F, I, L, O (P, C, F, K, O)	Major capsid protein VP1	polymer	300	32965.4	5	UniProt (P03088)	Betapolyomavirus hominis	Major structural protein VP1
4	AA, CB, IA, KB, P... (A, K, C, M, H...)	CHLORIDE ION	non-polymer		35.5	9	Chemie (CL)
5	CA, DA, EA, JA, MB... (B, C, M, H, E...)	TRIETHYLENE GLYCOL	non-polymer		150.2	9	Chemie (PGE)
6	AB, FB, GA, GB, HA... (J, K, B, C, D...)	1,2-ETHANEDIOL	non-polymer		62.1	23	Chemie (EDO)
7	BA, LB, RB, SB, U... (B, M, N, L, P)	TETRAETHYLENE GLYCOL	non-polymer		194.2	6	Chemie (PG4)
8	V, YA (L, J)	1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE	non-polymer		178.2	2	Chemie (PG5)
9	DB, EB, FA, NA, SA... (K, B, D, E, N...)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
10	WA (G)	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
11	BB (J)	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
12	AC, BC, CC, DC, EC... (A, B, C, D, E...)	water	water		18.0	2156	Chemie (HOH)

Sequence modifications

P, C, F, K, O: -24 - 275 (UniProt: P03088)

PDB	External Database	Details
Ser 80	Cys 105	engineered mutation
Asp 133	Glu 158	variant
Thr 146	Ser 171	variant
Thr 194	Ala 219	variant

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	402356.9
Non-Polymers*	Number of molecules	60
	Total formula weight	6095.7
All*	Total formula weight	408452.6

*Water molecules are not included.