9RHM

Phospho-MCM double hexamer bound to Sld3-Sld7-Cdc45 on ARS1 DNA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, R)	Mitochondrial morphogenesis protein SLD7	polymer	257	29598.8	2	UniProt (Q08457) Pfam (PF18636) Pfam (PF18596)	Saccharomyces cerevisiae (brewer's yeast)	Synthetic lethality with DPB11-24 mutation protein 7
2	B, F (H, I)	DNA replication regulator SLD3	polymer	704	81240.7	2	UniProt (P53135) Pfam (PF18523) Pfam (PF08639)	Saccharomyces cerevisiae (brewer's yeast)
3	D (X)	DNA (53-MER)	polymer	53	16326.4	1		Saccharomyces cerevisiae
4	E (Y)	DNA (53-MER)	polymer	53	16335.5	1		Saccharomyces cerevisiae
5	G (E)	Cell division control protein 45	polymer	657	75154.7	1	UniProt (Q08032) Pfam (PF02724)	Saccharomyces cerevisiae (brewer's yeast)
6	H, N (2, a)	DNA replication licensing factor MCM2	polymer	868	98911.5	2	UniProt (P29469) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae (brewer's yeast)	Minichromosome maintenance protein 2
7	I, O (3, b)	DNA replication licensing factor MCM3	polymer	1006	111720.2	2	UniProt (P24279) Pfam (PF22207) Pfam (PF23191) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae (brewer's yeast)	Minichromosome maintenance protein 3
8	J, P (4, c)	DNA replication licensing factor MCM4	polymer	933	105138.4	2	UniProt (P30665) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21128)	Saccharomyces cerevisiae (brewer's yeast)	Cell division control protein 54
9	K, Q (5, d)	Minichromosome maintenance protein 5	polymer	775	86505.7	2	UniProt (P29496) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933)	Saccharomyces cerevisiae (brewer's yeast)	Cell division control protein 46
10	L, R (6, e)	DNA replication licensing factor MCM6	polymer	1017	113110.2	2	UniProt (P53091) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263)	Saccharomyces cerevisiae (brewer's yeast)	Minichromosome maintenance protein 6
11	M, S (7, f)	DNA replication licensing factor MCM7	polymer	845	95049.9	2	UniProt (P38132) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF24901)	Saccharomyces cerevisiae (brewer's yeast)	Cell division control protein 47,Minichromosome maintenance protein 7
12	AA, BA, CA, GA, IA... (6, 7, a, c, d...)	ZINC ION	non-polymer		65.4	10	Chemie (ZN)
13	EA, HA, U, X (b, d, 3, 5)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)
14	DA, FA, V, Y (a, b, 3, 5)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG) PubChem (888)

Sequence modifications

H, I: 1 - 668 (UniProt: P53135)

PDB	External Database	Details
Glu 669	-	expression tag
Asn 670	-	expression tag
Leu 671	-	expression tag
Tyr 672	-	expression tag
Phe 673	-	expression tag
Gln 674	-	expression tag
Gly 675	-	expression tag
Trp 676	-	expression tag
Ser 677	-	expression tag
His 678	-	expression tag
Pro 679	-	expression tag
Gln 680	-	expression tag
Phe 681	-	expression tag
Glu 682	-	expression tag
Lys 683	-	expression tag
Gly 684	-	expression tag
Gly 685	-	expression tag
Gly 686	-	expression tag
Ser 687	-	expression tag
Gly 688	-	expression tag
Gly 689	-	expression tag
Gly 690	-	expression tag
Ser 691	-	expression tag
Gly 692	-	expression tag
Gly 693	-	expression tag
Ser 694	-	expression tag
Ser 695	-	expression tag
Ala 696	-	expression tag
Trp 697	-	expression tag
Ser 698	-	expression tag
His 699	-	expression tag
Pro 700	-	expression tag
Gln 701	-	expression tag
Phe 702	-	expression tag
Glu 703	-	expression tag
Lys 704	-	expression tag

E: 1 - 150 (UniProt: Q08032)
E: 151 - 650 (UniProt: Q08032)

PDB	External Database	Details
Asp 150	-	linker
Tyr 150	-	linker
Lys 150	-	linker
Asp 150	-	linker
Asp 151	-	linker
Asp 151	-	linker
Gly 151	-	linker
Asp 151	-	linker
Tyr 151	-	linker
Lys 151	-	linker
Asp 151	-	linker
Asp 151	-	linker
Asp 151	-	linker

3, b: 1 - 971 (UniProt: P24279)

PDB	External Database	Details
Met -34	-	initiating methionine
Lys -33	-	expression tag
Arg -32	-	expression tag
Arg -31	-	expression tag
Trp -30	-	expression tag
Lys -29	-	expression tag
Lys -28	-	expression tag
Asn -27	-	expression tag
Phe -26	-	expression tag
Ile -25	-	expression tag
Ala -24	-	expression tag
Val -23	-	expression tag
Ser -22	-	expression tag
Ala -21	-	expression tag
Ala -20	-	expression tag
Asn -19	-	expression tag
Arg -18	-	expression tag
Phe -17	-	expression tag
Lys -16	-	expression tag
Lys -15	-	expression tag
Ile -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Ala -9	-	expression tag
Leu -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Glu 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	19
	Total formula weight	1550367.6
Non-Polymers*	Number of molecules	18
	Total formula weight	2460.1
All*	Total formula weight	1552827.7

*Water molecules are not included.