9RHG
FZD7 in complex with negative allosteric modulator C407
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Frizzled-7 | polymer | 603 | 67460.9 | 2 | UniProt (O75084) | Homo sapiens (human) | Fz-7,hFz7,FzE3 |
| 2 | C, D, F, G (B, A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 4 | Chemie (Y01) | |||
| 3 | E (B) | ethyl 3-[2-[(2-fluorophenyl)amino]-2-oxidanylidene-ethyl]-5-methyl-4-oxidanylidene-thieno[2,3-d]pyrimidine-6-carboxylate | non-polymer | 389.4 | 1 | Chemie (A1JGQ) |
Sequence modifications
B, A: 33 - 574 (UniProt: O75084)
| PDB | External Database | Details |
|---|---|---|
| Met 10 | - | initiating methionine |
| Lys 11 | - | expression tag |
| Thr 12 | - | expression tag |
| Ile 13 | - | expression tag |
| Ile 14 | - | expression tag |
| Ala 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Tyr 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Phe 20 | - | expression tag |
| Cys 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Val 23 | - | expression tag |
| Phe 24 | - | expression tag |
| Ala 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Tyr 27 | - | expression tag |
| Lys 28 | - | expression tag |
| Asp 29 | - | expression tag |
| Asp 30 | - | expression tag |
| Asp 31 | - | expression tag |
| Asp 32 | - | expression tag |
| Ser 575 | - | expression tag |
| Arg 576 | - | expression tag |
| Leu 577 | - | expression tag |
| Glu 578 | - | expression tag |
| Val 579 | - | expression tag |
| Leu 580 | - | expression tag |
| Phe 581 | - | expression tag |
| Gln 582 | - | expression tag |
| Gly 583 | - | expression tag |
| Pro 584 | - | expression tag |
| Trp 585 | - | expression tag |
| Ser 586 | - | expression tag |
| His 587 | - | expression tag |
| Pro 588 | - | expression tag |
| Gln 589 | - | expression tag |
| Phe 590 | - | expression tag |
| Glu 591 | - | expression tag |
| Lys 592 | - | expression tag |
| Gly 593 | - | expression tag |
| Gly 594 | - | expression tag |
| Gly 595 | - | expression tag |
| Ser 596 | - | expression tag |
| Gly 597 | - | expression tag |
| Gly 598 | - | expression tag |
| Gly 599 | - | expression tag |
| Ser 600 | - | expression tag |
| Gly 601 | - | expression tag |
| Gly 602 | - | expression tag |
| Gly 603 | - | expression tag |
| Ser 604 | - | expression tag |
| Trp 605 | - | expression tag |
| Ser 606 | - | expression tag |
| His 607 | - | expression tag |
| Pro 608 | - | expression tag |
| Gln 609 | - | expression tag |
| Phe 610 | - | expression tag |
| Glu 611 | - | expression tag |
| Lys 612 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 134921.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2336.3 | |
| All* | Total formula weight | 137258.0 |
