9RDK
Cryo-EM structure of the human SAGA co-activator complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Transcription initiation factor TFIID subunit 9B | polymer | 251 | 27654.9 | 1 | UniProt (Q9HBM6) | Homo sapiens (human) | Neuronal cell death-related protein 7,DN-7,Transcription initiation factor TFIID subunit 9-like,Transcription-associated factor TAFII31L |
| 2 | B (N) | Ataxin-7 | polymer | 892 | 95597.7 | 1 | UniProt (O15265) | Homo sapiens (human) | Spinocerebellar ataxia type 7 protein |
| 3 | C (L) | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L | polymer | 589 | 66223.0 | 1 | UniProt (O75529) | Homo sapiens (human) | TAF5L,PCAF-associated factor 65 beta,PAF65-beta |
| 4 | D (A) | Splicing factor 3B subunit 3 | polymer | 1217 | 135718.8 | 1 | UniProt (Q15393) | Homo sapiens (human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 5 | E (C) | Transformation/transcription domain-associated protein | polymer | 3859 | 438139.5 | 1 | UniProt (Q9Y4A5) | Homo sapiens (human) | 350/400 kDa PCAF-associated factor,PAF350/400,STAF40,Tra1 homolog |
| 6 | F (D) | STAGA complex 65 subunit gamma | polymer | 414 | 46243.6 | 1 | UniProt (O94864) | Homo sapiens (human) | Adenocarcinoma antigen ART1,SPTF-associated factor 65 gamma,STAF65gamma,Suppressor of Ty 7-like |
| 7 | G (G) | Transcription initiation factor TFIID subunit 12 | polymer | 161 | 17948.5 | 1 | UniProt (Q16514) | Homo sapiens (human) | Transcription initiation factor TFIID 20/15 kDa subunits,TAFII-20/TAFII-15,TAFII20/TAFII15 |
| 8 | H (H) | Transcription initiation factor TFIID subunit 10 | polymer | 218 | 21731.2 | 1 | UniProt (Q12962) | Homo sapiens (human) | STAF28,Transcription initiation factor TFIID 30 kDa subunit,TAF(II)30,TAFII-30,TAFII30 |
| 9 | I (I) | Transcription initiation protein SPT3 homolog | polymer | 317 | 35840.8 | 1 | UniProt (O75486) | Homo sapiens (human) | SPT3-like protein |
| 10 | J (J) | Transcriptional adapter 1 | polymer | 335 | 37432.5 | 1 | UniProt (Q96BN2) | Homo sapiens (human) | SPT3-associated factor 42,STAF42,Transcriptional adapter 1-like protein |
| 11 | K (K) | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L | polymer | 622 | 67903.3 | 1 | UniProt (Q9Y6J9) | Homo sapiens (human) | TAF6L,PCAF-associated factor 65-alpha,PAF65-alpha |
| 12 | L (M) | Transcription factor SPT20 homolog | polymer | 779 | 85884.9 | 1 | UniProt (Q8NEM7) | Homo sapiens (human) | p38-interacting protein,p38IP |
| 13 | M (B) | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) | Homo sapiens (human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 1086468.2 | |
| All* | Total formula weight | 1086468.2 |
