9R3I
Structure of liver pyruvate kinase in complex with fluorescent probe 4c
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoform L-type of Pyruvate kinase PKLR | polymer | 447 | 48285.4 | 4 | UniProt (P30613) Pfam (PF00224) Pfam (PF02887) | Homo sapiens (human) | Pyruvate kinase 1,Pyruvate kinase isozymes L/R,R-type/L-type pyruvate kinase,Red cell/liver pyruvate kinase |
| 2 | E, F, H, I (A, B, C, D) | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) PubChem (16219368) PubChem (718) PubChem (10267) PubChem (172313) PubChem (24802138) PubChem (440117) PubChem (46937007) PubChem (5702629) PubChem (89534552) PubChem (445557) PubChem (92209485) PubChem (92209486) PubChem (12800340) PubChem (92209487) PubChem (124383956) PubChem (124540446) PubChem (135053794) PubChem (123134048) PubChem (124202619) PubChem (124427861) PubChem (124524513) PubChem (124604817) PubChem (130233858) PubChem (133126640) PubChem (135055131) PubChem (140434362) PubChem (146159004) PubChem (160510795) | |||
| 3 | G, J (C, D) | 4-[4-[[7-(dimethylamino)-2,1,3-benzoxadiazol-4-yl]sulfonyl]piperazin-1-yl]sulfonyl-5-pyridin-3-yl-benzene-1,2-diol | non-polymer | 560.6 | 2 | Chemie (A1JB2) PubChem (176490097) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 543 (UniProt: P30613)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 12 | Ser 12 | conflict |
| - | Glu 130 | deletion |
| - | Ile 131 | deletion |
| - | Arg 132 | deletion |
| - | Thr 133 | deletion |
| - | Gly 134 | deletion |
| - | Ile 135 | deletion |
| - | Leu 136 | deletion |
| - | Gln 137 | deletion |
| - | Gly 138 | deletion |
| - | Gly 139 | deletion |
| - | Pro 140 | deletion |
| - | Glu 141 | deletion |
| - | Ser 142 | deletion |
| - | Glu 143 | deletion |
| - | Val 144 | deletion |
| - | Glu 145 | deletion |
| - | Leu 146 | deletion |
| - | Val 147 | deletion |
| - | Lys 148 | deletion |
| - | Gly 149 | deletion |
| - | Ser 150 | deletion |
| - | Gln 151 | deletion |
| - | Val 152 | deletion |
| - | Leu 153 | deletion |
| - | Val 154 | deletion |
| - | Thr 155 | deletion |
| - | Val 156 | deletion |
| - | Asp 157 | deletion |
| - | Pro 158 | deletion |
| - | Ala 159 | deletion |
| - | Phe 160 | deletion |
| - | Arg 161 | deletion |
| - | Thr 162 | deletion |
| - | Arg 163 | deletion |
| - | Gly 164 | deletion |
| - | Asn 165 | deletion |
| - | Ala 166 | deletion |
| - | Asn 167 | deletion |
| - | Thr 168 | deletion |
| - | Val 169 | deletion |
| - | Trp 170 | deletion |
| - | Val 171 | deletion |
| - | Asp 172 | deletion |
| - | Tyr 173 | deletion |
| - | Pro 174 | deletion |
| - | Asn 175 | deletion |
| - | Ile 176 | deletion |
| - | Val 177 | deletion |
| - | Arg 178 | deletion |
| - | Val 179 | deletion |
| - | Val 180 | deletion |
| - | Pro 181 | deletion |
| - | Val 182 | deletion |
| - | Gly 183 | deletion |
| - | Gly 184 | deletion |
| - | Arg 185 | deletion |
| - | Ile 186 | deletion |
| - | Tyr 187 | deletion |
| - | Ile 188 | deletion |
| - | Asp 189 | deletion |
| - | Asp 190 | deletion |
| - | Gly 191 | deletion |
| - | Leu 192 | deletion |
| - | Ile 193 | deletion |
| - | Ser 194 | deletion |
| - | Leu 195 | deletion |
| - | Val 196 | deletion |
| - | Val 197 | deletion |
| - | Gln 198 | deletion |
| - | Lys 199 | deletion |
| - | Ile 200 | deletion |
| - | Gly 201 | deletion |
| - | Pro 202 | deletion |
| - | Glu 203 | deletion |
| - | Gly 204 | deletion |
| - | Leu 205 | deletion |
| - | Val 206 | deletion |
| - | Thr 207 | deletion |
| - | Gln 208 | deletion |
| - | Val 209 | deletion |
| - | Glu 210 | deletion |
| - | Asn 211 | deletion |
| - | Gly 212 | deletion |
| - | Gly 213 | deletion |
| - | Val 214 | deletion |
| - | Leu 215 | deletion |
| - | Gly 216 | deletion |
| - | Ser 217 | deletion |
| - | Arg 218 | deletion |
| - | Lys 219 | deletion |
| - | Gly 220 | deletion |
| - | Val 221 | deletion |
| - | Asn 222 | deletion |
| - | Leu 223 | deletion |
| - | Pro 224 | deletion |
| - | Gly 225 | deletion |
| - | Ala 226 | deletion |
| - | Gln 227 | deletion |
| Gly 130 | Val 228 | linker |
| Ser 131 | Asp 229 | linker |
| Gly 132 | Leu 230 | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 193141.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2481.7 | |
| All* | Total formula weight | 195623.2 |
