9R2E
Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (H, A) | ARGX-121 Fab fragment heavy chain | polymer | 244 | 25904.1 | 2 | Homo sapiens | ||
| 2 | B, F (L, B) | ARGX-121 Fab fragment light chain | polymer | 235 | 24725.7 | 2 | Homo sapiens | ||
| 3 | C, D (P, Q) | Isoform 1 of Immunoglobulin heavy constant alpha 1 | polymer | 213 | 23155.3 | 2 | UniProt (P01876) Pfam (PF00047) Pfam (PF07654) | Homo sapiens (human) | Ig alpha-1 chain C region,Ig alpha-1 chain C region BUR,Ig alpha-1 chain C region TRO |
| 4 | G, H, N, Q (H, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | I, J, M, O, P (H, L, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | K, L, R (L, P, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | S, T, U, V, W... (H, L, P, Q, A...) | water | water | 18.0 | 377 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 147570.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 851.8 | |
| All* | Total formula weight | 148421.9 |
