9R27

Regorafenib in complex with p38alpha (MAPK14)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069)	Homo sapiens (human)	MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a
2	B (A)	octyl beta-D-glucopyranoside	non-polymer		292.4	1	Chemie (BOG)
3	C (A)	4-[4-[[4-chloranyl-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluoranyl-phenoxy]-~{N}-methyl-pyridine-2-carboxamide	non-polymer		482.8	1	Chemie (A1JCR)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	2
	Total formula weight	775.2
All*	Total formula weight	42118.4

*Water molecules are not included.