9QY8

Crystal structure of apoform human USP18

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubl carboxyl-terminal hydrolase 18,Response regulator FrzS	polymer	440	49748.4	2	UniProt (Q9UMW8) UniProt (Q1D4U9) Pfam (PF00443) Pfam (PF00072)	Homo sapiens (human)	43 kDa ISG15-specific protease,hUBP43,ISG15-specific-processing protease,Ubl thioesterase 18
2	C, D (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
3	E, F (A, B)	water	water		18.0	223	Chemie (HOH)

Sequence modifications

A, B: 49 - 285 (UniProt: Q9UMW8)

PDB	External Database	Details
Gly 47	-	expression tag
Pro 48	-	expression tag

A, B: 403 - 526 (UniProt: Q1D4U9)

PDB	External Database	Details
Gly 527	-	linker
Ser 528	-	linker

A, B: 300 - 372 (UniProt: Q9UMW8)

PDB	External Database	Details
Gly 401	-	linker
Ser 402	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99496.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	99627.6

*Water molecules are not included.