9QVT
Crystal structure of STING CTD in complex with potent agonist D5
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 242 | 27154.6 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | 4-[6-methoxy-5-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzothiophen-5-yl]sulfanylmethylsulfanyl]-1-benzothiophen-2-yl]-4-oxidanylidene-butanoic acid | non-polymer | 604.7 | 1 | Chemie (A1JA0) | |||
| 3 | C (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 138 - 379 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Ser 139 | Leu 139 | engineered mutation |
| Arg 232 | His 232 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27154.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 604.7 | |
| All* | Total formula weight | 27759.3 |
