9QUB

Cryo-EM structure of the human NHA2-Fab complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, E)	Fab-light chain	polymer	214	23715.1	2		Mus musculus
2	C, D (D, F)	Fab-heavy chain	polymer	256	27757.5	2		Mus musculus
3	E, F (B, A)	Sodium/hydrogen exchanger 9B2	polymer	537	57611.7	2	UniProt (Q86UD5) Pfam (PF00999)	Homo sapiens (Human)	Na(+)/H(+) exchanger NHA2,Na(+)/H(+) exchanger-like domain-containing protein 2,NHE domain-containing protein 2,Sodium/hydrogen exchanger-like domain-containing protein 2,Solute carrier family 9 subfamily B member 2
4	G, H (B, A)	2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE	non-polymer		648.9	2	Chemie (LPP)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	218168.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1297.8
All*	Total formula weight	219466.4

*Water molecules are not included.