9QOB
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound 4
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 126 | 15012.3 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | B, C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D (A) | (5-phenyl-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl)methanol | non-polymer | 231.3 | 1 | Chemie (A1I8D) | |||
| 4 | E (A) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 43 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | Thr 43 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15012.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 355.4 | |
| All* | Total formula weight | 15367.7 |
