9QAM
Human angiotensin-1 converting enzyme C-domain in complex with ciprofloxacin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Angiotensin-converting enzyme, soluble form | polymer | 578 | 66763.6 | 1 | UniProt (P12821) Pfam (PF01401) | Homo sapiens (human) | |
| 2 | B (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 3 | C (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-1-deoxy-alpha-D-mannopyranose | branched | 367.3 | 1 | In PDB | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | G (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 7 | H (A) | N-CARBOXYALANINE | non-polymer | 133.1 | 1 | Chemie (NXA) | |||
| 8 | I (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 9 | J, K (A) | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID | non-polymer | 331.3 | 2 | Chemie (CPF) | |||
| 10 | L, M (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 11 | N (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 12 | O (A) | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A: 40 - 617 (UniProt: P12821)
| PDB | External Database | Details |
|---|---|---|
| Gly 64 | Glu 669 | engineered mutation |
| Gln 90 | Asn 695 | engineered mutation |
| Gln 123 | Glu 728 | engineered mutation |
| Gln 155 | Asn 760 | engineered mutation |
| Gln 337 | Asn 942 | engineered mutation |
| Gln 586 | Asn 1191 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66763.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 937.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1333.5 | |
| All* | Total formula weight | 69035.0 |
