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9QA5

Structure of the N-SH2 domain of SHP2 in complex with the phosphoY627-Gab1 (613-651) peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 3 of Tyrosine-protein phosphatase non-receptor type 11polymer10612006.51UniProt (Q06124)
Pfam (PF00017)
Homo sapiens (human)Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,SHP-2,Shp2,SH-PTP3
2B
(B)
GRB2-associated-binding protein 1polymer394223.61UniProt (Q13480)Homo sapiensGRB2-associated binder 1,Growth factor receptor bound protein 2-associated protein 1
3C, D
(A, B)
waterwater18.043Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight16230.1
All*Total formula weight16230.1
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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