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9Q5Y

Human prolyl endopeptidase (PREP) - complex with YX45

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Prolyl endopeptidasepolymer71180851.43UniProt (P48147)
Pfam (PF02897)
Pfam (PF00326)
Homo sapiens (human)PE,Post-proline cleaving enzyme
2D
(A)
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer282.31Chemie (B3P)
3E, M, W
(A, B, C)
2-[4-chloro-1-(2-phenylethyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1-(pyrrolidin-1-yl)ethan-1-onenon-polymer368.93Chemie (A1CQR)
4AA, CA, EA, F, G...
(C, A, B)
GLYCEROLnon-polymer92.120Chemie (GOL)
5BA, DA, H, Q
(C, A, B)
DI(HYDROXYETHYL)ETHERnon-polymer106.14Chemie (PEG)
6FA, GA, HA
(A, B, C)
waterwater18.01975Chemie (HOH)
Sequence modifications
A, B, C: 1 - 710 (UniProt: P48147)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight242554.1
Non-Polymers*Number of molecules28
Total formula weight3655.3
All*Total formula weight246209.4
*Water molecules are not included.

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PDB entries from 2026-01-28

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