9Q4D

A DARPin fused to the double trigger 1TEL variant crystallization chaperone via a direct helical fusion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription factor ETV6,DARPin	polymer	243	27095.3	1	UniProt (P41212) Pfam (PF02198)	Homo sapiens (human)
2	B, C, D, E, F... (A)	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
3	I, J, K, L (A)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
4	M (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
5	N (A)	water	water		18.0	187	Chemie (HOH)

Sequence modifications

A: 12 - 86 (UniProt: P41212)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Glu 61	Leu 96	engineered mutation
Glu 77	Val 112	engineered mutation

A: 87 - 242 (PDB: 9Q4D)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27095.3
Non-Polymers*	Number of molecules	12
	Total formula weight	615.4
All*	Total formula weight	27710.7

*Water molecules are not included.