9Q3N
Crystal structure of human CDK5-cyclinB1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Cyclin-dependent kinase 5 | polymer | 295 | 33622.7 | 1 | UniProt (Q00535) | Homo sapiens (human) | Cell division protein kinase 5,Cyclin-dependent-like kinase 5,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit |
| 2 | B (C) | G2/mitotic-specific cyclin-B1 | polymer | 285 | 32497.7 | 1 | UniProt (P14635) | Homo sapiens (human) | |
| 3 | C, F (B, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | D, E, H, I, J (B, C) | polyethylene glycol | non-polymer | 662.8 | 5 | Chemie (P4K) PubChem (76871872) | |||
| 5 | G (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | K, L (B, C) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
B: 1 - 292 (UniProt: Q00535)
C: 152 - 433 (UniProt: P14635)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 149 | - | expression tag |
| Asn 150 | - | expression tag |
| Ala 151 | - | expression tag |
| Ser 167 | Cys 167 | engineered mutation |
| Ser 238 | Cys 238 | engineered mutation |
| Ser 350 | Cys 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66120.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3598.2 | |
| All* | Total formula weight | 69718.6 |
