9PZB
HCMV trimer in complex with E4K, E11K, A9K, E9L, E8K, B1K, E7K, F12L and E10L Fabs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Envelope glycoprotein H | polymer | 743 | 84538.6 | 1 | UniProt (Q69155) | Human betaherpesvirus 5 | |
| 2 | B (B) | Envelope glycoprotein L | polymer | 268 | 29877.3 | 1 | UniProt (Q8JP80) | Human betaherpesvirus 5 | gL |
| 3 | C (D) | E10L Fab light chain | polymer | 111 | 11679.7 | 1 | Homo sapiens | ||
| 4 | D (E) | E10L Fab heavy chain | polymer | 122 | 13452.1 | 1 | Homo sapiens | ||
| 5 | E (F) | A9K Fab heavy chain | polymer | 116 | 12993.5 | 1 | Homo sapiens | ||
| 6 | F (G) | A9K Fab light chain | polymer | 107 | 11597.9 | 1 | Homo sapiens | ||
| 7 | G (H) | E8K Fab heavy chaun | polymer | 126 | 14369.0 | 1 | Homo sapiens | ||
| 8 | H (I) | E8K Fab light chain | polymer | 113 | 12477.9 | 1 | Homo sapiens | ||
| 9 | I (J) | F12L Fab heavy chain | polymer | 118 | 12956.5 | 1 | Homo sapiens | ||
| 10 | J (K) | F12L Fab light chain | polymer | 115 | 12438.8 | 1 | Homo sapiens | ||
| 11 | K (L) | E9L Fab light chain | polymer | 107 | 11461.6 | 1 | Homo sapiens | ||
| 12 | L (M) | E9L Fab heavy chaun | polymer | 118 | 13016.7 | 1 | Homo sapiens | ||
| 13 | M (N) | B1K Fab heavy chain | polymer | 117 | 12984.4 | 1 | Homo sapiens | ||
| 14 | N (O) | B1K Fab light chain | polymer | 107 | 11566.9 | 1 | Homo sapiens | ||
| 15 | O (P) | E4K Fab heavy chain | polymer | 121 | 13517.1 | 1 | Homo sapiens | ||
| 16 | P (Q) | E4K Fab light chain | polymer | 108 | 11741.2 | 1 | Homo sapiens | ||
| 17 | Q, R, S (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) PubChem (24139) |
Sequence modifications
A: 0 - 742 (UniProt: Q69155)
B: 31 - 278 (UniProt: Q8JP80)
| PDB | External Database | Details |
|---|---|---|
| Thr 12 | Ala 13 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Val 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Thr 15 | - | expression tag |
| Gln 16 | - | expression tag |
| Val 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Leu 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Trp 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Thr 26 | - | expression tag |
| Asp 27 | - | expression tag |
| Ala 28 | - | expression tag |
| Arg 29 | - | expression tag |
| Cys 30 | - | expression tag |
| Glu 41 | Lys 41 | engineered mutation |
| Arg 77 | Gly 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 290669.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 291332.9 |
