9PUO
Neutralizing monoclonal antibody Fab fragment bound to leptin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Neutralizing antibody Fab fragment, heavy chain | polymer | 225 | 23681.6 | 2 | Homo sapiens | ||
| 2 | B, E (B, E) | Neutralizing antibody Fab fragment, light chain | polymer | 217 | 22933.3 | 2 | Homo sapiens | ||
| 3 | C, F (C, F) | Leptin | polymer | 146 | 15984.3 | 2 | UniProt (P41159) Pfam (PF02024) | Homo sapiens (human) | Obese protein,Obesity factor |
| 4 | G, H (D) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) |
Sequence modifications
C, F: 1 - 146 (UniProt: P41159)
| PDB | External Database | Details |
|---|---|---|
| Glu 100 | Trp 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 125198.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 125388.3 |
