Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-1 receptor-associated kinase 4 | polymer | 304 | 34135.5 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | E, F, I, K (A, B, C, D) | N-[(1R,5S,8R)-3-(5-{(6P)-6-[(8S)-3-cyanopyrrolo[1,2-b]pyridazin-7-yl]-4-[(propan-2-yl)amino]pyridin-3-yl}-1,3,4-thiadiazol-2-yl)-3-azabicyclo[3.2.1]octan-8-yl]acetamide | non-polymer | 527.6 | 4 | Chemie (A1CKS) | |||
| 3 | G, H, J (B, C) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 160 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Gly 157 | - | expression tag |
| Ala 158 | - | expression tag |
| Met 159 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 136542.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2398.8 | |
| All* | Total formula weight | 138940.9 |
