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9PSS

IRAK4 in Complex with Compound 3

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Interleukin-1 receptor-associated kinase 4polymer30434215.52UniProt (Q9NWZ3)
Pfam (PF07714)
Homo sapiens (human)IRAK-4,Renal carcinoma antigen NY-REN-64
2C, F
(A, B)
(7P,8S)-7-{(5M)-5-[1-(oxan-4-yl)-1H-1,2,3-triazol-4-yl]-4-[(propan-2-yl)amino]pyridin-2-yl}pyrrolo[1,2-b]pyridazine-3-carbonitrilenon-polymer428.52Chemie (A1CKP)
3D, E, G
(A, B)
SULFATE IONnon-polymer96.13Chemie (SO4)
4H, I
(A, B)
waterwater18.0204Chemie (HOH)
Sequence modifications
A, B: 160 - 460 (UniProt: Q9NWZ3)
PDBExternal DatabaseDetails
Gly 157-expression tag
Ala 158-expression tag
Met 159-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight68431.0
Non-Polymers*Number of molecules5
Total formula weight1145.2
All*Total formula weight69576.2
*Water molecules are not included.

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PDB entries from 2026-02-25

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