9PRW
Cryo-EM structure of human DNMT3A/3L
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | DNA (cytosine-5)-methyltransferase 3A | polymer | 633 | 72297.8 | 2 | UniProt (Q9Y6K1) Pfam (PF00855) Pfam (PF17980) Pfam (PF21255) Pfam (PF00145) | Homo sapiens (human) | Dnmt3a,Cysteine methyltransferase DNMT3A,DNA methyltransferase HsaIIIA,DNA MTase HsaIIIA,M.HsaIIIA |
| 2 | B, C (B, C) | DNA (cytosine-5)-methyltransferase 3-like | polymer | 386 | 43630.8 | 2 | UniProt (Q9UJW3) Pfam (PF17980) Pfam (PF21255) | Homo sapiens (human) | |
| 3 | E, O (A, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | F, G, H, I, J... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) |
Sequence modifications
A, D: 281 - 912 (UniProt: Q9Y6K1)
| PDB | External Database | Details |
|---|---|---|
| Ser 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 231857.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1553.7 | |
| All* | Total formula weight | 233410.9 |
