9PQ1
The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation Inhibitors
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor XI | polymer | 625 | 70201.1 | 1 | UniProt (P03951) Pfam (PF00024) Pfam (PF00089) | Homo sapiens (human) | FXI,Plasma thromboplastin antecedent,PTA |
| 2 | B (B) | Kininogen-1 light chain | polymer | 12 | 1340.4 | 1 | UniProt (P01042) | Homo sapiens | |
| 3 | C (C) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 4 | D (A) | {6-[(1,2,3-benzothiadiazol-5-yl)methoxy]-4-(piperidine-1-carbonyl)quinolin-2-yl}[4-(1H-pyrazol-1-yl)piperidin-1-yl]methanone | non-polymer | 581.7 | 1 | Chemie (A1CJA) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) PubChem (24139) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71541.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 802.9 | |
| All* | Total formula weight | 73093.1 |
