9PLP
Crystal structure of netrin-1 in complex with anti-netrin-1 Fab (NP137 Fab)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Netrin-1 | polymer | 443 | 49579.9 | 2 | UniProt (Q90922) | Gallus gallus (chicken) | |
| 2 | C, E (C, H) | NP137 Fab heavy chain | polymer | 222 | 23460.3 | 2 | Mus musculus (mouse) | ||
| 3 | D, F (D, L) | NP137 Fab light chain | polymer | 225 | 24671.5 | 2 | Mus musculus (mouse) | ||
| 4 | G, H (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) |
Sequence modifications
A, B: 26 - 458 (UniProt: Q90922)
| PDB | External Database | Details |
|---|---|---|
| Ala 22 | - | insertion |
| Pro 23 | - | insertion |
| Leu 24 | - | insertion |
| Ala 25 | - | insertion |
| Gly 459 | - | expression tag |
| Ser 460 | - | expression tag |
| Leu 461 | - | expression tag |
| Val 462 | - | expression tag |
| Pro 463 | - | expression tag |
| Arg 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 195423.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 195503.6 |
