9PLP
Crystal structure of netrin-1 in complex with anti-netrin-1 Fab (NP137 Fab)
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CdCkhNtaGPeC |
| Chain | Residue | Details |
| A | CYS306-CYS317 | |
| A | CYS425-CYS436 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| C | TYR196-HIS202 |
| site_id | PS01248 |
| Number of Residues | 35 |
| Details | EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cd.CkhntaGpeCdrCkpfhYdrpwqratareane.C |
| Chain | Residue | Details |
| A | CYS306-CYS340 | |
| A | CYS370-CYS406 | |
| A | CYS425-CYS453 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 110 |
| Details | Domain: {"description":"Laminin EGF-like 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 124 |
| Details | Domain: {"description":"Laminin EGF-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00460","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
