9PLN

Locally-refined structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (R)	Alpha-2A adrenergic receptor	polymer	491	53643.9	1	UniProt (P08913) Pfam (PF00001)	Homo sapiens (human)	Alpha-2 adrenergic receptor subtype C10,Alpha-2A adrenoreceptor,Alpha-2A adrenoceptor,Alpha-2AAR
2	B (R)	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	non-polymer		234.3	1	Chemie (A1CIU)

Sequence modifications

R: 2 - 465 (UniProt: P08913)

PDB	External Database	Details
Met -25	-	expression tag
Lys -24	-	expression tag
Thr -23	-	expression tag
Ile -22	-	expression tag
Ile -21	-	expression tag
Ala -20	-	expression tag
Leu -19	-	expression tag
Ser -18	-	expression tag
Tyr -17	-	expression tag
Ile -16	-	expression tag
Phe -15	-	expression tag
Cys -14	-	expression tag
Leu -13	-	expression tag
Val -12	-	expression tag
Phe -11	-	expression tag
Ala -10	-	expression tag
Asp -9	-	expression tag
Tyr -8	-	expression tag
Lys -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Ala -2	-	expression tag
Ser -1	-	expression tag
Ile 0	-	expression tag
Asp 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53643.9
Non-Polymers*	Number of molecules	1
	Total formula weight	234.3
All*	Total formula weight	53878.2

*Water molecules are not included.