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9PFR

Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) in NTP-bound elongation state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-directed RNA polymerase Lpolymer2165250704.51UniProt (P28887)Respiratory syncytial virusProtein L,Large structural protein,Replicase,Transcriptase
2B, C, D, E
(B, C, D, E)
Phosphoproteinpolymer24127165.84UniProt (G3C7Q7)Respiratory syncytial virus
3F
(P)
RNA (5'-R(P*AP*CP*G)-3')polymer3934.61Respiratory syncytial virus A2
4G
(T)
RNA (5'-R(P*UP*UP*UP*UP*UP*UP*CP*UP*CP*GP*U)-3')polymer123666.11Respiratory syncytial virus A2
5H
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
6I
(A)
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosinenon-polymer506.21Chemie (ZAN)
PubChem (10074905)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight363968.6
Non-Polymers*Number of molecules2
Total formula weight530.5
All*Total formula weight364499.1
*Water molecules are not included.

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PDB entries from 2026-05-06

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