9PD2

Crystal structure of PILRA in complex with Fab portion of antagonist antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Paired immunoglobulin-like type 2 receptor alpha	polymer	151	17769.9	1	UniProt (Q9UKJ1) Pfam (PF07686)	Homo sapiens (human)	Cell surface receptor FDF03,Inhibitory receptor PILR-alpha
2	B (H)	Anti-PILRA Fab Heavy Chain	polymer	225	23977.9	1		Homo sapiens (human)
3	C (L)	Anti-PILRA Fab Light Chain	polymer	214	23558.1	1		Homo sapiens (human)
4	D, E, F (A, H, L)	water	water		18.0	27	Chemie (HOH)

Sequence modifications

A: 32 - 150 (UniProt: Q9UKJ1)

PDB	External Database	Details
Met 0	-	initiating methionine
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Gly 9	-	expression tag
Leu 10	-	expression tag
Asn 11	-	expression tag
Asp 12	-	expression tag
Ile 13	-	expression tag
Phe 14	-	expression tag
Glu 15	-	expression tag
Ala 16	-	expression tag
Gln 17	-	expression tag
Lys 18	-	expression tag
Ile 19	-	expression tag
Glu 20	-	expression tag
Trp 21	-	expression tag
His 22	-	expression tag
Glu 23	-	expression tag
Leu 24	-	expression tag
Glu 25	-	expression tag
Val 26	-	expression tag
Leu 27	-	expression tag
Phe 28	-	expression tag
Gln 29	-	expression tag
Gly 30	-	expression tag
Pro 31	-	expression tag
Gly 78	Arg 78	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65305.9
All*	Total formula weight	65305.9

*Water molecules are not included.