9PB5
Human TRPM8 menthol bound structure at 4 degrees Celsius resolved in cell vesicles using cryo-EM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily M member 8 | polymer | 1111 | 128334.2 | 4 | UniProt (Q7Z2W7) | Homo sapiens (human) | Long transient receptor potential channel 6,LTrpC-6,LTrpC6,Transient receptor potential p8,Trp-p8 |
| 2 | E, F, G, H (A, B, C, D) | (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol | non-polymer | 156.3 | 4 | Chemie (XUQ) |
Sequence modifications
A, B, C, D: 1 - 1104 (UniProt: Q7Z2W7)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 513336.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 625.1 | |
| All* | Total formula weight | 513961.9 |
