9PB5
Human TRPM8 menthol bound structure at 4 degrees Celsius resolved in cell vesicles using cryo-EM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily M member 8 | polymer | 1111 | 128334.2 | 4 | UniProt (Q7Z2W7) Pfam (PF18139) Pfam (PF25508) Pfam (PF00520) | Homo sapiens (human) | Long transient receptor potential channel 6,LTrpC-6,LTrpC6,Transient receptor potential p8,Trp-p8 |
| 2 | E, F, G, H (A, B, C, D) | (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol | non-polymer | 156.3 | 4 | Chemie (XUQ) PubChem (1715097) PubChem (1254) PubChem (23617692) PubChem (16666) PubChem (19243) PubChem (19244) PubChem (165675) PubChem (57110971) PubChem (439263) PubChem (67414864) PubChem (67988893) PubChem (67988905) PubChem (68026467) PubChem (45056) PubChem (5319369) PubChem (6432468) PubChem (6566020) PubChem (11228933) PubChem (11815981) PubChem (12039947) PubChem (12076118) PubChem (12141429) PubChem (12285346) PubChem (12285347) PubChem (12285348) PubChem (12285349) |
Sequence modifications
A, B, C, D: 1 - 1104 (UniProt: Q7Z2W7)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 513336.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 625.1 | |
| All* | Total formula weight | 513961.9 |
