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9PAR

Avian TRPM8 (Parus major) semi-swapped, ligand-free structure at high pH and 4 degrees Celsius resolved in GDN using cryo-EM

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 8polymer1101127217.04UniProt (A0A5S8WF66)Parus major (Great Tit)
2E, F, G, H
(A, B, C, D)
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoatenon-polymer1047.14Chemie (PT5)
PubChem (46891800)
Sequence modifications
A, B, C, D: 2 - 1095 (UniProt: A0A5S8WF66)
PDBExternal DatabaseDetails
Gly -6-expression tag
Pro -5-expression tag
Gly -4-expression tag
Ser -3-expression tag
Gly -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
Met 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight508868.1
Non-Polymers*Number of molecules4
Total formula weight4188.4
All*Total formula weight513056.4
*Water molecules are not included.

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PDB entries from 2026-03-25

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