9OVV
Heteromeric GluA1/A2-CNIH1 in the activated state, composite map of LBD-TMD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Isoform Flip of Glutamate receptor 1 | polymer | 431 | 48285.3 | 2 | UniProt (P19490) | Rattus norvegicus (Norway rat) | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1 |
| 2 | B, D (B, D) | Isoform Flip of Glutamate receptor 2 | polymer | 428 | 47767.0 | 2 | UniProt (P19491) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2 |
| 3 | E, F, G, H (E, F, G, H) | Protein cornichon homolog 1 | polymer | 142 | 16489.6 | 4 | UniProt (O95406) | Homo sapiens (human) | CNIH-1,Cornichon family AMPA receptor auxiliary protein 1,Protein cornichon homolog,T-cell growth-associated molecule 77,TGAM77 |
| 4 | I, O, U, Z (A, B, C, D) | GLUTAMIC ACID | non-polymer | 147.1 | 4 | Chemie (GLU) PubChem (611) PubChem (23327) PubChem (33032) | |||
| 5 | AA, BA, CA, DA, EA... (D, E, A, B, C) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 16 | Chemie (POV) PubChem (65167) PubChem (5497103) PubChem (6436017) PubChem (6506401) PubChem (10908846) PubChem (168614) PubChem (6070971) | |||
| 6 | M, T (A, B) | N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | non-polymer | 480.7 | 2 | Chemie (FWF) PubChem (22259901) PubChem (44468130) PubChem (44468131) | Rattus norvegicus (Norway rat) | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1 | |
| 7 | N (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) |
Sequence modifications
B, D: 392 - 819 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gln 392 | Asn 413 | conflict |
| Arg 586 | Gln 607 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 258063.1 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 13734.1 | |
| All* | Total formula weight | 271797.2 |
