9OT6
Cryo-EM structure of the PI4KA complex bound to an EFR3 interfering nanobody (F3IN)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 4-kinase alpha | polymer | 2104 | 237246.4 | 2 | UniProt (P42356) Pfam (PF19274) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (human) | PI4-kinase alpha,PI4K-alpha,PtdIns-4-kinase alpha,Phosphatidylinositol 4-Kinase III alpha |
| 2 | C, H (C, H) | EFR3 interfering Nanobody (F3IN) | polymer | 165 | 18025.2 | 2 | Lama glama | ||
| 3 | D, F (D, F) | Tetratricopeptide repeat protein 7B | polymer | 843 | 94294.1 | 2 | UniProt (Q86TV6) Pfam (PF19440) Pfam (PF13181) Pfam (PF12895) Pfam (PF13424) | Homo sapiens (human) | TPR repeat protein 7B,Tetratricopeptide repeat protein 7-like-1,TPR repeat protein 7-like-1 |
| 4 | E, G (E, G) | Hyccin | polymer | 308 | 34638.9 | 2 | UniProt (Q9BYI3) Pfam (PF09790) | Homo sapiens (human) | Down-regulated by CTNNB1 protein A |
Sequence modifications
A, B: 1 - 2102 (UniProt: P42356)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 768409.3 | |
| All* | Total formula weight | 768409.3 |
