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9OS2

Cryo-EM structure of the DDB1/CRBN-MRT-5702-G3BP2 ternary complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Protein cereblonpolymer37843554.11UniProt (Q96SW2)Homo sapiens (human)
2B
(A)
DNA damage-binding protein 1polymer1140127097.51UniProt (Q16531)Homo sapiens (human)DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
3C, D
(C, D)
Ras GTPase-activating protein-binding protein 2polymer48254198.12UniProt (Q9UN86)Homo sapiens (human)G3BP-2,GAP SH3 domain-binding protein 2
4E
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
5F
(B)
(1S,3S)-2-[(2-chlorophenyl)methanesulfonyl]-N-{[(4R)-3-(2,4-dioxo-1,3-diazinan-1-yl)imidazo[1,2-a]pyridin-7-yl]methyl}-1-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamidenon-polymer621.11Chemie (A1CED)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight279047.7
Non-Polymers*Number of molecules2
Total formula weight686.5
All*Total formula weight279734.2
*Water molecules are not included.

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PDB entries from 2026-01-28

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