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9OS2

Cryo-EM structure of the DDB1/CRBN-MRT-5702-G3BP2 ternary complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Protein cereblonpolymer37843554.11UniProt (Q96SW2)
Pfam (PF02190)
Pfam (PF03226)
Homo sapiens (human)
2B
(A)
DNA damage-binding protein 1polymer1140127097.51UniProt (Q16531)
Pfam (PF10433)
Pfam (PF23726)
Pfam (PF03178)
Homo sapiens (human)DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe
3C, D
(C, D)
Ras GTPase-activating protein-binding protein 2polymer48254198.12UniProt (Q9UN86)
Pfam (PF02136)
Pfam (PF00076)
Homo sapiens (human)G3BP-2,GAP SH3 domain-binding protein 2
4E
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
5F
(B)
(1S,3S)-2-[(2-chlorophenyl)methanesulfonyl]-N-{[(4R)-3-(2,4-dioxo-1,3-diazinan-1-yl)imidazo[1,2-a]pyridin-7-yl]methyl}-1-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamidenon-polymer621.11Chemie (A1CED)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight279047.7
Non-Polymers*Number of molecules2
Total formula weight686.5
All*Total formula weight279734.2
*Water molecules are not included.

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PDB entries from 2026-02-04

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