9OPY

Structure of the sweet receptor in the apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Taste receptor type 1 member 2	polymer	818	92842.0	1	UniProt (Q8TE23) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Homo sapiens (human)	G protein-coupled receptor 71,Sweet taste receptor T1R2
2	B (B)	Taste receptor type 1 member 3	polymer	838	92648.6	1	UniProt (Q925D8) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003)	Mus musculus (house mouse)	Saccharin preference protein,Sweet taste receptor T1R3

Sequence modifications

A: 22 - 839 (UniProt: Q8TE23)

PDB	External Database	Details
Ser 132	Ile 132	engineered mutation
Asn 212	Ser 212	engineered mutation
Gly 231	Asp 231	engineered mutation

B: 23 - 835 (UniProt: Q925D8)

PDB	External Database	Details
Ala 21	-	expression tag
Ser 22	-	expression tag
Gly 836	-	expression tag
Arg 837	-	expression tag
Asn 838	-	expression tag
Ala 839	-	expression tag
Lys 840	-	expression tag
Lys 841	-	expression tag
Ala 842	-	expression tag
Ala 843	-	expression tag
Asp 844	-	expression tag
Glu 845	-	expression tag
Asn 846	-	expression tag
Ser 847	-	expression tag
Gly 848	-	expression tag
Gly 849	-	expression tag
Gly 850	-	expression tag
Glu 851	-	expression tag
Ala 852	-	expression tag
Ala 853	-	expression tag
Gln 854	-	expression tag
Gly 855	-	expression tag
His 856	-	expression tag
Asn 857	-	expression tag
Glu 858	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	185490.6
All*	Total formula weight	185490.6

*Water molecules are not included.