9OPY
Structure of the sweet receptor in the apo state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007165 | biological_process | signal transduction |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0008527 | molecular_function | taste receptor activity |
| A | 0016020 | cellular_component | membrane |
| A | 0032467 | biological_process | positive regulation of cytokinesis |
| A | 0033041 | molecular_function | sweet taste receptor activity |
| A | 0043235 | cellular_component | receptor complex |
| A | 0050909 | biological_process | sensory perception of taste |
| A | 0050916 | biological_process | sensory perception of sweet taste |
| A | 1903767 | cellular_component | sweet taste receptor complex |
| B | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007165 | biological_process | signal transduction |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0008527 | molecular_function | taste receptor activity |
| B | 0033041 | molecular_function | sweet taste receptor activity |
| B | 0050909 | biological_process | sensory perception of taste |
| B | 0050916 | biological_process | sensory perception of sweet taste |
| B | 0050917 | biological_process | sensory perception of umami taste |
| B | 1903767 | cellular_component | sweet taste receptor complex |
Functional Information from PROSITE/UniProt
| site_id | PS00980 |
| Number of Residues | 25 |
| Details | G_PROTEIN_RECEP_F3_2 G-protein coupled receptors family 3 signature 2. CCYdCvdCkagsYrkhp.DdfTCtpC |
| Chain | Residue | Details |
| B | CYS522-CYS546 | |
| A | CYS513-CYS538 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 96 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 82 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 17 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; when associated with variant T-60","evidences":[{"source":"PubMed","id":"11326277","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
