9OC6

Crystal structure of receptor FcRn bound to Human Astrovirus 6 spike

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	IgG receptor FcRn large subunit p51	polymer	274	30408.1	1	UniProt (P55899) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	FcRn,IgG Fc fragment receptor transporter alpha chain,Neonatal Fc receptor
2	B (D)	Beta-2-microglobulin	polymer	99	11748.2	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C (A)	Capsid polyprotein VP90	polymer	244	27929.4	1	UniProt (A0A3G6VE58)	Human astrovirus 6

Sequence modifications

A: 2 - 216 (UniProt: A0A3G6VE58)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 217	-	expression tag
Ser 218	-	expression tag
Gly 219	-	expression tag
Leu 220	-	expression tag
Asn 221	-	expression tag
Asp 222	-	expression tag
Ile 223	-	expression tag
Phe 224	-	expression tag
Glu 225	-	expression tag
Ala 226	-	expression tag
Gln 227	-	expression tag
Lys 228	-	expression tag
Ile 229	-	expression tag
Glu 230	-	expression tag
Trp 231	-	expression tag
His 232	-	expression tag
Glu 233	-	expression tag
Gly 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70085.6
All*	Total formula weight	70085.6

*Water molecules are not included.