9OAR

Crystal structure of antibody Fab G001-179 from IAVI G001 human trial in complex with a germline-targeting gp120 engineered outer domain eOD-GT8-mingly

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (C, A)	Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8-mingly	polymer	183	19889.2	2		Homo sapiens (human)
2	B, E (H, B)	G001-179 Fab heavy chain	polymer	227	24180.1	2		Homo sapiens (human)
3	C, F (L, D)	G001-179 Fab light chain	polymer	210	22998.4	2		Homo sapiens (human)
4	G, H, I, J (C, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	K, L, M, N, O... (C, H, L, A, B...)	water	water		18.0	1642	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	134135.6
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	135020.4

*Water molecules are not included.